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As gorgeous as they may be, high heels that are made out of non-pliable, man-made, synthtic material like plastic and vinyl will almost always cause blisters and burning. Be sure the heels are made from real leather or suede, both of which are soft, pliable and able to mold to the natural shape of your foot. This small detail has the ability to drastically reduce blisters, swelling and foot pain — and may be why many quality-made, higher priced shoes really are more comfortable.